Tea consumption and risk of endometrial cancer: a metaanalysis

Posted: 5 February 2010
Categroy: Independent Research
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The objective of the study was to assess the association between tea consumption and endometrial cancer.

Na-Ping Tang, MD; Hua Li, MD; Yun-Liang Qiu, MD; Guo-Min Zhou, PhD; Jing Ma, PhD

OBJECTIVE:

The objective of the study was to assess the association between tea consumption and endometrial cancer.

STUDY DESIGN:

Studies were identiﬁed by searching PubMed and EMBASE databases and screening the references of retrieved articles. The summary rel- ative risk (RR) with 95% conﬁdence interval (CI) was calculated.

RESULTS:

The combined RR for ever drinkers vs non/lowest drinkers was 0.85 (95% CI, 0.77– 0.94). Compared with non/lowest drinkers, the summary RR was 0.88 (95% CI, 0.78 – 0.98) for low to moderate drinkers and 0.75 (95% CI, 0.64 – 0.88) for high drinkers. An increase in tea intake of 2 cups/day was associated with a 25% decreased risk of endometrial cancer. In subgroup analyses, tea consumption was signif- icantly associated with reduced endometrial cancer risk in Asian studies and studies using interviewing techniques. Furthermore, the protective effect of green tea on endometrial cancer seemed more evident than that of black tea.

CONCLUSION:

Findings from this metaanalysis suggest that tea con- sumption may reduce the risk of endometrial cancer. Because of the limited number of studies, further prospective studies are needed to ex- plore the protective effect of tea on endometrial cancer.

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